The Tendon transplant to work in a cross-band OP

In many cases, a SURGERY after a cruciate ligament tear is useful. Often, the cruciate ligament is replaced by the graft by a Tendon. As the OP runs out and what to keep in mind after the Operation.

An adverse movement, a sound like a whip, and a sudden pain, a ligament tear, sometimes faster than many suspect. The two cruciate ligaments are actually very robust, because they play for the stability of the knee joint has an important role: Together with the Outer and inner band forming the ligamentous apparatus of the knee joint, the knee with each movement and strengthens.

Seen from the side, the two bands intersect – therefore, you will have your name. A cross band runs from the Shin bone down the front to the thigh bone obliquely upward and backward (anterior cruciate ligament), the other one from the Shin from the bottom rear of the thigh obliquely to the front upper (posterior cruciate ligament). You have to prevent the femur sliding too far backwards and the Shin bone too far forward. Is one of the bands ripped (cruciate ligament rupture), can only produce an Operation with the necessary stability in the knee joint.

After an injury, and is suspected to have a ligament tear you should definitely go to the doctor. This can clarify with the patient what therapy is for a cure is necessary. Conservative methods, such as a targeted muscle building through physiotherapy, in each case, necessary in order to strengthen the knee after the injury. However, a pure muscle – building can replace alone, never a broken cross-band that shows the statistics: over 90 percent of the patient’s instability in the knee joint after sole treatment with conservative methods still.

About the author

Norbert Wynands is a specialist in surgery, accident surgery and sports medicine. He is senior physician of the Department of trauma and reconstructive surgery at the red cross hospital in Lindenberg.

Although the healing from the physical condition of the Person and your personal claim to your physical activity, the person Concerned, however: The younger and the more active, the more recommend is a surgery in which the ligament is replaced. With the following operational method of a cruciate ligament rupture can be treated.

Cross-band SURGERY with tendon graft

A virtually universal method of operation of the cruciate ligament by a tendon graft, the tendon of the thigh muscle (semitendinosus tendon, or quadriceps) or the patellar tendon of the patient is taken. The latter is the connection between the lower leg and kneecap. This minimally invasive, arthroscopic surgery (single-bundle reconstruction) is now one of the Standard methods of treatment and can be done up to one year after the injury.

When the Operation is first removed through a small incision in the replacement tendon. This is about a twenty to thirty centimeters long tendon is then placed four on top of each other, so that you are reduced to a quarter of the length and their tensile strength is significantly increased. Then be drilled in both the femur and in the tibia bone a small, approximately two-centimeter-long channels. By this, the two Ends are pulled tendon Replacement, tensioned and then fixed. The aim is that the replacement tendon in the subsequent conservation phase, with the bone fully fuses, so that the function of the cruciate ligament is largely restored.

Fasten the cross band set with a tear-resistant thread

The Fixation of the cruciate ligament set can be done using various techniques. One of these is the “Tight Rope”method is: The replacement tendon is pulled with a particularly tear-resistant medical thread (Tight Rope) by hauling technique in the drilled bone channels – first through the channel in the leg rail, then into the channel in the femur. This type of pulley allows the replacement tendon to take up slack in the best possible way.

In order to fix the string on the thigh bone, rolling papers, a small Metal about the filament introduced. As soon as the tendon was pulled through the top of the bone canal, the leaves on the outer side of the femur. Now it has a larger surface than the Radius of the drilled bone channel and thereby prevents a sliding Back of the cross-band set. Subsequently, the tendon is tensioned, and on the outer side of the opposite Shin bone is fixed with a screw.

With the time, the thread and the replacement tendon around the fabric, the Replacement ligament is based. In the subsequent conservation phase, the Tendon axes with the bone. The screw loosens over time, the metal flakes and the thread will remain in the knee of the patient.

Physical therapy is a Must

After a cruciate ligament tear should be waiting with the Operation until the knee of the patients want to completely off, and also is pain-free. Only then is it possible that the cruciate ligament replace the normal proportions of the Body. Often, concomitant injuries associated with cruciate ligament tears such as a meniscus tear. These are also only in a worn woolen knee completely visible and need to be treated in order to obtain an intact joint.

Even if surgery, everything runs optimally, can be replaced the function of the natural cruciate ligament, never to 100 percent. However, it can be manufactured by means of a minimally invasive procedure and the relevant volume set, the stability of the knee joint.

Without an accompanying physiotherapy and without the will of the patient, regain mobility and strength in the leg, but. Those who make the effort and diligently by the skilled person recommended, and injury to and healing degree of coordinated Exercises, therefore, has the prospect to be able to his knee after six to eight months to fully re-charge. An external knee brace (orthosis) is the patient in everyday life also safety, and prevents Twisting of the knee.

lasmiditan

INDIANAPOLIS, Nov. 14, 2018 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) has announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for lasmiditan for the acute treatment of migraine with or without aura in adults.

Lasmiditan is an investigational, oral, centrally-penetrant, selective serotonin 5-HT1F agonist that is structurally and mechanistically distinct from other approved migraine therapies and lacks vasoconstrictive activity. It is the first and only molecule in the "-ditan" class under evaluation for the acute treatment of migraine in adults. If approved, it could represent the first significant innovation for the acute treatment of migraine in more than two decades.

The NDA for lasmiditan includes data from two Phase 3 single-attack studies (SAMURAI and SPARTAN), which evaluated the safety and efficacy of lasmiditan for the acute treatment of migraine. In both studies, at two hours following the first dose of lasmiditan, the percentage of patients who were migraine pain-free was significantly greater compared to placebo. These results were significant across all studied doses. Lasmiditan also met the key secondary endpoint, with a significantly greater percentage of patients free of their most bothersome symptom (MBS) compared with placebo at two hours following the first dose. In these studies, patients chose their MBS from sensitivity to light, sensitivity to sound or nausea. The most commonly reported adverse events after lasmiditan dosing were dizziness, paresthesia, somnolence, fatigue, nausea, muscle weakness and numbness. Data from these studies were presented at the American Headache Society (AHS) annual meeting and the American Academy of Neurology (AAN) annual meeting.

About Migraine

Migraine is a disabling, neurologic disease characterized by recurrent episodes of severe headache accompanied by other symptoms including nausea, vomiting, sensitivity to light and sound, and changes in vision.1,2 More than 30 million American adults have migraine, with three times more women affected by migraine compared to men.3,4,5,6 According to the Medical Expenditures Panel Survey, the total unadjusted cost associated with migraine in the U.S. is estimated to be as high as $56 billion annually, yet migraine remains under-recognized and under-treated.3,7,8

About Lasmiditan

Lasmiditan is an investigational, first-in-class molecule under evaluation for the acute treatment of migraine. Lasmiditan uses a novel mechanism of action which selectively targets 5-HT1F receptors, including those expressed in the trigeminal pathway, and has been designed for the acute treatment of migraine without the vasoconstrictor activity associated with some migraine therapies. Data from two Phase 3 single-attack studies (SAMURAI and SPARTAN) have been presented at the American Headache Society (AHS) annual meeting and the American Academy of Neurology (AAN) annual meeting. In March 2017, Lilly completed the acquisition of CoLucid Pharmaceuticals, including lasmiditan, which was originally discovered at Lilly.

About Lilly's Commitment to Headache Disorders

For over 25 years, Lilly has been committed to helping people suffering from headache disorders, investigating more than a dozen different compounds for the treatment of migraine, cluster headache and other disabling headache disorders. These research programs have accelerated the understanding of these diseases and furthered the advancement of Lilly's comprehensive late-stage development programs studying galcanezumab-gnlm for prevention of migraine and cluster headache, and lasmiditan for the acute treatment of migraine. Our goal is to make life better for people with headache disorders by offering comprehensive solutions to prevent or stop these disabling diseases. The combined clinical, academic and professional experience of our experts helps us to build our research portfolio, identify challenges for healthcare providers and pinpoint the needs of patients living with migraine and cluster headache.

About Eli Lilly and Company

Lilly is a global healthcare leader that unites caring with discovery to make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at www.lilly.com and www.lilly.com/newsroom/social-channels.  P-LLY

This press release contains forward-looking statements (as that term is defined in the Private Securities Litigation Reform Act of 1995) about Emgality (galcanezumab-gnlm) as a treatment for patients with migraine and as a potential treatment for patients with episodic cluster headaches; lasmiditan as a potential treatment for patients with migraine; and tanezumab as a potential treatment for patients with osteoarthritis, chronic low back pain and cancer pain and reflects Lilly's current belief. However, as with any pharmaceutical product, there are substantial risks and uncertainties in the process of development and commercialization. Among other things, there can be no guarantee that Emgality, lasmiditan or tanezumab will receive additional regulatory approvals. There can also be no guarantee that any of these molecules will be commercially successful. For further discussion of these and other risks and uncertainties, see Lilly's most recent Form 10-K and Form 10-Q filings with the United States Securities and Exchange Commission. Except as required by law, Lilly undertakes no duty to update forward-looking statements to reflect events after the date of this release.

SOURCE Eli Lilly & Company

Posted: November 2018

lasmiditan FDA Approval History

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Why natural depression therapies are better than pills

Winter is upon us. And with it comes the annual worsening of depressive symptoms. Sadly, in the United States, suicide continues to claim more lives than firearms, and suicide rates are increasing in nearly all states. The U.S. Centers for Disease Control and Prevention reports that death by suicide has increased by 30 per cent since 1999 and a similar trend is observed in Canada.

I was distressed but not surprised to learn that these increases occurred over a period of time in which use of antidepressants skyrocketed by 65 per cent. By 2014, around one in eight Americans over the age of 12 reported recent antidepressant use.

I practice critical-care medicine in Guelph, Ontario. Sadly, 10 to 15 per cent of my practice is the resuscitation and life support of suicide and overdose patients.

It is not uncommon for these patients to have overdosed on the very antidepressants they were prescribed to prevent such a desperate act. The failures of antidepressants are a clear and present part of my clinical experience.

Wedded to drugs that barely work

Ten years ago, when finishing medical school, I carefully considered going into psychiatry. Ultimately, I was turned off by my impression that thought leaders in psychiatry were mistakenly wedded to a drug treatment that barely works.

A 2004 review by the Cochrane Foundation found that when compared against an “active” placebo (one that causes side effects similar to antidepressants), antidepressants were statistically of almost undetectable benefit.

Studies that compared antidepressants to “dummy” placebos showed larger but still underwhelming results. On the 52-point Hamilton Depression Rating Scale (HDRS), patients who took the antidepressants fluoxetine (Paxil) or venlafaxine (Effexor) experienced an average decrease of 11.8 points, whereas those taking the placebo experienced an average decrease of 9.6 points.

I am not suggesting that antidepressants do not work. I am suggesting that they are given a precedence in our thinking about mental health that they do not deserve.

I leave it to readers to look at the Hamilton Depression Rating Scale and decide for themselves whether a drop of 2.5 points is worth taking a pill with myriad potential side effects including weight gain, erectile dysfunction and internal bleeding.

It might be, but do note that taking an antidepressant does not seem to decrease the risk of suicide.

Natural therapies that work

The far more exciting and underplayed point, to me, is that multiple non-drug treatments have been shown to be as effective. As a staunch critic of alternative medical regimes such as chiropractic, acupuncture and homeopathy, it surprises me to note that the following “natural” therapies have rigorous, peer-reviewed scientific studies to support their use:

1. Exercise

In 2007, researchers at Duke University Medical Center in North Carolina randomly assigned patients to 30 minutes of walking or jogging three times a week, a commonly prescribed antidepressant (Zoloft), or placebo. Their results? Exercise was more effective than pills!

A 2016 review of all the available studies of exercise for depression confirms it: Exercise is an effective therapy. And it’s free!

2. Bright light therapy

You know how you just feel better after an hour out in the sun? There probably is something to it. Bright light therapy is an effort to duplicate the sun’s cheering effects in a controlled fashion. Typically, patients are asked to sit in front of a “light box” generating 10,000 Lux from 30 to 60 minutes first thing in the morning.

A review of studies using this therapy showed significant effect. The largest study showed a 2.5 point drop on the HDRS, roughly equal to that seen from antidepressants.

The sun gives 100,000 lux on a clear day and I can’t think of a reason why sunlight itself wouldn’t work, weather permitting.

3. Mediterranean diet

This one surprised me when it came out last year. Researchers in Australia randomly assigned depressed patients to receive either nutritional counselling or placebo social support.

The nutritionists recommended a Mediterranean diet, modified to include local unprocessed foods.

Thirty-two per cent of the depressed dieters experienced remission versus eight per cent of those who only received social support, a far larger effect than seen in antidepressant trials.

4. Cognitive Behavioural Therapy (CBT)

This is the best recognized of the “natural” treatments for depression and the evidence is indisputable.

CBT is as effective as antidepressants but more expensive in the short term. However, antidepressants stop working when you stop taking them, whereas the benefits of CBT seem to last.

And as an aside, it is very difficult to overdose fatally on a bottle of therapy.

I freely admit that the trials I have mentioned are smaller than the major antidepressant trials. But whereas antidepressants are projected to bring in almost $17 billion a year for the pharmaceutical industry globally by 2020, the jogging and sunlight industries will never have the resources to fund massive international trials. With this in mind, I am convinced that they are at least as worthwhile as the pills.

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Pancreatic cancer death rates rising across Europe, report reveals

Pancreatic cancer death rates in the European Union (EU) have increased by 5% between 1990 and 2016, a report launched today reveals. This is the highest increase in any of the EU’s top five cancer killers which, as well as pancreatic cancer, includes lung, colorectal, breast and prostate cancer.

‘Pancreatic Cancer Across Europe’, published by United European Gastroenterology (UEG) to coincide with World Pancreatic Cancer Day, examines the past and current state of pancreatic cancer care and treatment, as well as the future prospects, such as targeting the microbiome, for improving the prognosis for patients. Whilst lung, breast and colorectal cancer have seen significant reductions in death rates since 1990, deaths from pancreatic cancer continue to rise. Experts also believe that pancreatic cancer has now overtaken breast cancer as the third leading cause of death from cancer in the EU.

Pancreatic cancer has the lowest survival of all cancers in Europe. Responsible for over 95,000 EU deaths every year, the median survival time at the point of diagnosis is just 4.6 months, with patients losing 98% of their healthy life expectancy5. Often referred to as ‘the silent killer’, symptoms can be hard to identify, thus making it difficult to diagnose the disease early which is essential for life-saving surgery.

Despite the rise in death rates and dreadfully low survival rates, pancreatic cancer receives less than 2% of all cancer research funding in Europe. Markus Peck, UEG expert, explains, “If we are to take a stand against the continent’s deadliest cancer, we must address the insufficient research funding; that is where the European Union can lead the way. Whilst medical and scientific innovations have positively changed the prospects for many cancer patients, those diagnosed with pancreatic cancer have not been blessed with much clinically meaningful progress. To deliver earlier diagnoses and improved treatments we need to engage now in more basic as well as applied research to see real progress for our patients in the years to come.”

Microbiome—the key to turning the tide?

After forty years of limited progress in pancreatic cancer research, experts claim that new treatment options could finally be on the horizon as researchers investigate how changing the pancreas’ microbiome may help to slow tumour growth and enable the body to develop its own ‘defence mechanism’. The microbial population of a cancerous pancreas has been found to be approximately 1,000 times larger than that of a non-cancerous pancreas and research has shown that removing bacteria from the gut and pancreas slowed cancer growth and ‘reprogrammed’ immune cells to react against cancer cells.

This development could lead to significant changes in clinical practice as removing bacterial species could improve the efficacy of chemotherapy or immunotherapy, offering hope that clinicians will finally be able to slow tumour growth, alter metastatic behaviour and ultimately change the disease’s progression.

Professor Thomas Seufferlein, pancreatic cancer expert, comments, “Research looking at the impact of the microbiome on pancreatic cancer is a particularly exciting new area, as the pancreas was previously thought of as a sterile organ. Such research will also improve our understanding of the microenvironment in a metastatic setting and how the tumour responds to its environment. This will inform the metastatic behaviour and ultimately alter disease progression.”

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Why some people overeat when they’re upset

The idea of eating a tub of ice cream to cope with being upset has become a bit cliche. Though some might not need a tub of chocolate swirl to help perk themselves up again, there do seem to be systematic differences in the way that people cope with upsetting events, with some more likely to find solace in food than others.

This matters because when eating to cope with negative feelings is part of a broader tendency to overeat, it is likely to be associated with obesity and being overweight. More people than ever are now overweight and obese, with recent estimates suggesting that by 2025, 2.7 billion adults worldwide will be affected by obesity, risking health issues such as cardiovascular disease, type 2 diabetes and cancer.

So why do some people manage their emotions with food while others don’t? One psychological concept that helps to explain this difference is adult attachment orientation. Depending on the extent to which we fear abandonment by those we love, adults fall somewhere on the dimension of “attachment anxiety”. Where we fall on this dimension (high or low) determines a set of expectations about how we and others behave in personal relationships. These are developed as a response to the care we received as an infant and this can characterise your attachment style.

A recent meta-analysis – a study bringing together the results of many other studies – showed that the higher a person’s attachment anxiety, the more they engage in unhealthy eating behaviours, with a knock-on effect on body mass index (BMI). Two other studies have also shown that patients undergoing weight loss surgery are likely to have higher attachment anxiety scores than a comparable lean population, and it is thought that this difference is partly explained by the tendency to overeat.

Understanding attachment anxiety

For a long time, we have known that people who are have high attachment anxiety are more likely to both notice upsetting things and find it harder to manage their emotions when upset. This is because of how attachment orientations come about in the first place. The dynamics and feelings relating to our most important long-term relationships, including in early life, act as a templates that guide our behaviour in subsequent relationships and in stressful situations.

If we receive consistent care from a caregiver, which includes helping us to cope with problems in life, we develop a secure attachment orientation. For people high in security, when a negative life event occurs, they are able to seek support from others or soothe themselves by thinking about the sorts of things that their caregiver or other significant person would say to them in that situation.

However, inconsistent care – where the caregiver sometimes responds to another’s needs but at other times does not – leads to attachment anxiety and a fear that our needs won’t be met. When negative life events occur, support from others is sought but perceived as unreliable. People with high attachment anxiety are also less able to self-soothe than people with a secure attachment.

We recently tested whether this poor emotional management could explain why people with attachment anxiety are more likely to overeat. Importantly, we found that for people high in attachment anxiety it was harder to disengage from whatever was upsetting them and to get on with what they were supposed to be doing. These negative emotions were managed with food and this related to a higher BMI.

It is important to note, however, that this is only one factor among many that can influence overeating and BMI. We cannot say that attachment anxiety causes overeating and weight gain. It might be that overeating and weight gain influences our attachment orientation, or it could be a bit of both.

Managing eating behaviour

There are two approaches that appear promising for attachment anxious individuals seeking to manage their eating behaviour. These involve targeting the specific attachment orientation itself and/or improving emotion regulation skills in general.

To target attachment orientation, one possibility is a psychological technique called “security priming” designed to make people behave like “secures”, who cope well with negative life events. It results in beneficial effects more generally, such as engaging in more pro-social behaviours. One study showed that priming is related to snack intake. When people are asked to reflect on secure relationships in their life they eat less in a later snacking episode than when asked to reflect on anxious relationships in their life (though this work is very preliminary and needs replicating and extending).

Looking at emotion regulation, a recently published paper highlighted the importance of emotional eaters focusing on skills such as coping with stress rather than calorie restriction, when seeking to lose weight. This study did not look solely at those with attachment anxiety, however, so further work is needed explore this further.

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Tasteless food is bad for the psyche

The need to live in conditions, when a person is forced to eat tasteless food can harm the health of the psyche, the scientists from Israel. According to their conclusion, tasteless, monotonous food harmful for the psyche – it can cause severe depression and other disorders.

The experts stated: if the person does not like the food he uses and he considers it to be tasteless, it may lead to the development of mental health problems – depression, apathy, bouts of severe fatigue, or uncontrollable outbreaks of irritation and aggression. According to scientists, with a system consumption of tasteless food, the body loses the nutrients that are necessary for the proper functioning of the internal organs and nervous system.

The most negative is bad and tasteless food affects people who already suffer from various disorders depressive properties, said the researchers. In risk in women who often eat tasteless food for them in order to lose weight and slimness, experts say. For the female psyche monotonous and poor diet in particular is harmful because women are initially more susceptible to developing emotional disorders.

Those who eat monotonous and tasteless, often lack the vitamins, minerals, enzymes and other nutrients that come from food, say the authors of the project. In addition, the lack of variety in the diet suppresses the appetite and reduces taste sensitivity.

Earlier Magicforum wrote about how dangerous to health food at night.

Chemists prove chromones are effective against Alzheimer’s disease

RUDN chemists synthesized a range of biologically active molecules called chromones and demonstrated their use in the treatment of Alzheimer’s disease. The results of the work were published in the Bioorganic & Medicinal Chemistry journal.

Alzheimer’s disease is a progredient form of dementia causing irreversible deterioration of cognitive functions (attention, memory, orientation, and thinking) and resulting in complete disintegration of personality. According to the World Health Association, about 6-7 million people are diagnosed with Alzheimer’s disease annually. RUDN chemists with their colleagues from IPAC RAS and Lomonosov MSU synthesized new compounds that are able to stop the progression of this disease and studied their biological activity.

Alzheimer’s disease is associated with the damage of the central or peripheral nervous system. A special role in the work of the nervous system is played by a neurotransmitter called acetylcholine that helps a neural impulse move between neurons and then from neurons to muscles. Reduced levels of acetylcholine are one of the symptoms of Alzheimer’s disease. Today’s treatment methods are reduced to prolonging the activity of the remaining acetylcholine with drugs that slow down its disintegration and partially compensate for its loss.

The disintegration of acetylcholine is affected by several substances. The main role in the process is played by acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). In the course of development of the Alzheimer’s it’s the activity of BChE that increases. By reducing it, one may slow down the disintegration of acetylcholine. RUDN chemists managed to achieve this effect using chromones—biologically active molecules that have been previously successfully used in the treatment of other conditions. In their previous works the authors suggested a new way of synthesizing substituted chromones compounds, and in this research demonstrated their potential as an efficient anti-Alzheimer’s therapy.

“We found chromones interesting because of their pharmacological activity. Their derivatives appeared to have anti-cancer, anti-viral (including anti-HIV), anti-microbial, anti-fungal, anti-inflammatory, anti-diabetic, and antioxidant properties. It was especially important for our studies that chromones and their derivatives played an important role as antioxidants and acceptors of radicals,” said Larisa Kulikova, a candidate of chemistry, and a lecturer of the Faculty of Physics, Mathematics, and Natural Sciences at RUDN.

To evaluate the pharmacological activity of the obtained substances, the scientists used kinetic methods and modeling. The results of screenings showed that the new substances efficiently slowed down the activity of BChE. In the future the team hopes to improve the synthesis method and to obtain chemical compounds with antioxidant as well as BChE-suppressing properties. A substance like that would be able to slow down BChE and at the same time to reduce the so-called oxidative stress—the disbalance between the number of active oxygen or nitrogen compounds and the inability of the body to process them leading to massive cell death.

More information:
Galina F. Makhaeva et al. Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer’s disease therapeutics, Bioorganic & Medicinal Chemistry (2018). DOI: 10.1016/j.bmc.2018.08.010

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Hands must be protected at any cold

First in the cold and suffer in the cold hands. If the hands are nipped by the frost, it may lead to the exacerbation of chronic pathological processes in the body. Hands must be protected by any degree of cold, and even when zero not to be lazy to wear gloves or mittens, said the doctor, Victoria Savitskaya.

According to Savitskaya, the cold skin is expose to the wind and flakes, making them more vulnerable to harmful influence of cold. Should be aware of this and protect hands in cold weather, recommended the expert.

“On the palms and the hands are bioactive points associated with the head and respiratory system. Freezing hands can worsen chronic inflammation of the nose, bronchi, begin headaches,” – said the expert.
She also added that the cold is dangerous to hand that down to the cold they may experience inflammation of the small joints of the fingers and hands. Savitskaya urged to protect hands from the ravages of cold, at a temperature of from minus 10 to be sure to wear thick warm mittens, and don’t forget the gloves when the temperature is 0 degrees. She said: after a single freezing hands in them impaired thermoregulation for the whole cold season.

Earlier Magicforum wrote about what measures can save health with a sharp cold.

Bill Linanne: Magic is knowing when you have it good…and being able to enjoy it

You just can’t beat a good magic road. There are a couple of them scattered around Ireland, but the closest one to where I live – and therefore the best – is at Mahon Falls in west Waterford.

It’s hard to describe a magic road on paper, as they are effectively a grand illusion created by the collision of human endeavour – in the form of a road – and a landscape that refuses to conform to our sense of perspective. Basically, you think you’re going downhill, but you’re going uphill. You stop the car, put down the handbrake and roll up a slope. It sound ludicrous, but you really need to experience one for yourself, as even for a profound cynic like me, they inspire the same reaction that Fr Dougal had when he was told about one by Fr Ted – “this is almost as mad as that thing you told me about the loaves and fishes”.

Last Easter, in a feeble effort to instill some wonder in my kids, I decided to bring them to the local magic road. On the way there, I regaled them with tales of how amazing it is, dressing it up with some ludicrous guff about soft places where the walls between worlds were pliable and faerie folk were able to pass through. This, I explained, was why the magic road was marked with a faerie tree, a wiry windswept bush adorned with a selection of rags.

When people say there is no magic left in the world, they might be right, as some nihilist prankster cut down the faerie tree that marked where the magic road is. And so it was that I went crawling through the six-kilometre route, becoming increasingly frustrated that I was unable to find the blasted road. Perhaps its magical power is invisibility, I japed, as my children repeatedly asked where the magic road – which I had clearly oversold – was. Attempting to summon it by swearing in front of my children didn’t work, nor did looping through the entire drive a second time. Adding to my frustrations was the fact that my gearbox was acting up. Completely bothered, I drove home. It was only when I got home and angrily googled where the damn road had gone that I realised that my car wasn’t acting up, it was in fact the magic road that I was on, and I was, accordingly, in the wrong gear. Of course, I should have known exactly where it was, as I had been there previously, albeit two decades before.

Back in 1996, I went to Mahon Falls with my mum, dad and sister. We did the magic road, marvelled at the beauty of the falls, and came home. It would be the last day all four of us would spend together. Two weeks later, my sister suffered a heart attack brought on by her epilepsy, and died aged 22. She had been sick for more than half her life, to the point where I can hardly remember what she was like before the illness came.

I never really understood what my parents went through until my own daughter was diagnosed with an incurable autoimmune condition, and I find myself living in the house I grew up in, sleeping in what was my parents’ room, with a sick daughter who sleeps in my sister’s room. It sometimes feels like I am repeating history, stuck on an endless loop until I gain a deeper understanding of what it was like for my parents to have a sick child. I think I am finally starting to understand, decades too late, how much they and my sister went through.

I brought my kids back to Mahon Falls in the summer, and this time we found the magic road. They were completely unimpressed. “What’s magic about it? It’s just a road,” they asked. Magic, I informed them, was being able to discern when you are facing what you might think was an uphill battle, but you were in fact travelling downhill in the wrong gear, simply because you lacked perspective. Magic was knowing when you have it good, and being able to enjoy it, because some day it may slip away from you. The magic, I solemnly intoned, was that we were there together, that we had each other.

It turned out that real magic is knowing that you are talking to yourself, as your kids have stopped listening to you, just as you didn’t listen to your own parents.

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“I was obsessed with exercise I didn't realise I had a problem”

When fitness Instagrammer Sarah Rav, 20, was pulled aside by the dean of the hospital where she was studying, she never thought it might be because of her weight.

“Obviously I knew I was underweight but when I looked in the mirror, it didn’t click that I was unhealthily underweight. I’ve always been on the small side,” explains Sarah.

What happened next would change Sarah’s approach to health and fitness dramatically. Sarah explains that her medical supervisor took her aside:

“He said, ‘look, there’s been concerns about your health from your tutors, your fellow students, your friends and from your teachers. They’ve reached out to me, and they said they noticed that you look really unwell and that you’ve just been really down.”

The dean went on to advise that she take some time off from university and come back once she’d seen her GP and got a medical clearance.

“Initially I thought that’s kind of weird but if that’s what I need to do, then I’d do it. I didn’t realise I had a problem at the time,” explains Sarah. “But when I saw my GP, she was pretty shocked. She weighed me (I weighed30kg at the time), and she said, ‘You need to go to the hospital tonight’.”

It was hearing the diagnosis of Orthorexia (an obsession with exercising) that made Sarah realise that she had to make some changes. Up until that point she had been running 15-20km a day, returning with her feet bleeding and exhausted, and had a ‘fear of food’ she felt were unhealthy.

After a week in hospital, however, where they monitored her because they were worried her heart might stop, she set about on a six-month program to bring her back to being a normal weight for her height and build.

“In my mind, after I was diagnosed, I was like ‘I am obviously doing things wrong. This is not the way that I should be thinking. This is unhealthy,’ ” explains Sarah.

“Given that I got into health and fitness to be healthy, it made a lot of sense that I had to fix myself.”

On the advice of experts, she stopped working out for three months and followed a pretty strict meal plan. “Something that was challenging but ultimately rewarding,” says Sarah.

“It was hard [on the meal plan] because I hadn’t had bread or carbs in three to four months maybe; I had to eat white rice with meatballs. And I was like ‘oh my God’,” remembers Sarah. “But then, at the same time, I knew that I needed to do it to get better.”

That was a year ago and now for Sarah, she’s more aware than ever how easy it is to become obsessed with being healthy and fit to the point that you become sick. Her approach to life now is all about balance.

“I don’t follow any sort of set diet anymore. No calorie counting. It’s literally ‘eat what I want to eat’. Eat when I’m hungry. If I want white bread over wholegrain bread, I’ll go for it. If I want pancakes, I’ll go for it. And then, with exercise, it’s just only for my enjoyment,” she explains.  

It’s an approach she’s careful to share with her 1.7 million followers every day.

“Before all this happened, I was posting about fitness transformations and fitness info about ‘girls with abs’,” Sarah remembers. “But now I shy away from all of that and I post things that don’t focus on appearance so much as what your body can actually do, as well as other aspects [of health and fitness] that aren’t weight or appearance.”

The feedback from this shift and from Sarah’s health journey has been nothing but positive – something that she was worried about when she was first diagnosed.

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“The secret to having it all is knowing you already do” 💖 – Not gonna lie. It’s been a tough couple of weeks. Kinda been feeling like I’ve been getting no where. Kinda been feeling like I’ve been stuck in a rut. Kinda been feeling like nothing I do makes a difference. 😓 – But you know what? I took a moment today to write down every single thing that I am grateful for & 2hrs later, I’m still going 📝 . Essentially I realised I have SO MUCH to be grateful for and even though things aren’t going my way right now, that doesn’t mean that I haven’t already achieved and have been given SO MUCH. 🌟🎁 – So when things get tough, or you feel that life is treating you unfairly, take a little moment to think about just how much you actually have! 🙏🏽 (friends, family, your health, enough clothes, enough food & water….) . I could go on and on, but hopefully this makes you lift your head a little higher and smile a little brighter ☺️💖🤟🏽

A post shared by Previously @fitandfiesty (@sarahrav) on

“At first, I was really, really worried about coming out about it on Instagram because, in my mind I was like I can’t believe I have this [issue]. I didn’t want to tell anyone because I thought people are going to blame me for doing this to myself,” explains Sarah. “But once I came out, the reactions were so positive. Everyone has been so supportive and it just makes me realise that [struggling with] mental health isn’t as bad as what we perceive it to be. It’s definitely something that should be talked about more often, more openly.” 

And that’s why Sarah would like to share her story with others.

“My ultimate goal from this arduous journey is to help even just one single person with an eating disorder or mental illness – to make them understand that they are not alone, that they can get through this… and that they deserve recovery and happiness. If I can do that, then it makes everything I’ve been through worth it.”

If you are worried about yourself or someone in your care, the best thing you can do is talk to someone. Please contact the Butterfly Foundation 1800 33 4673 or chat online.

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