5 rules that will not let diabetes

The incidence of diabetes can be prevented in 80% of cases, it was stated by the acting Minister of health Suprun. According to her, 50% of cases of type 2 diabetes people living with him, not knowing that they are sick, for this disease characterized by long duration without showing critical symptoms.

The expert said about what rules are necessary to avoid getting diabetes.

Rule 1: balanced diet. According to the doctor, is particularly at risk with respect to the risk of diabetes is the consumption of high-calorie foods that are high in sugar and different additives. In addition, you should abandon or minimize the quantity of processed food – sausages, products made from white flour and rice.

Not to diabetes, it is important to eat fiber – vegetables and fruits. The expert was advised to eat regularly legumes – they are a regular presence on the table allows you to eat less calories not to gain weight and to have the minimum risk of developing diabetes.

Rule 2: maintain a healthy weight. Suprun stressed that obesity and a larger waist is the evidence of insulin resistance, which is developing prediabetes and then diabetes. Fat affects the maintenance of levels of sugar and cholesterol in the blood, so it is important to stay at one weight and not to gain weight. The greater the share of body fat, the higher the risk of diabetes.

Rule 3: be physically active. You must use any possibility for movements. Weekly body should get about 150 minutes of aerobic activity of moderate character or 75 minutes of intense exercise.

Rule 4: do not smoke. Scientific evidence suggests that smokers are 30-40% more likely to develop type 2 diabetes than non smokers. The risk of diabetes in smokers is higher due to the fact that substances from cigarette smoke getting to them in the body, causing inflammation, damage and oxidation of cells.

Rule 5: be examined. If some people in my family are diabetics, it is vital to check the blood sugar level and seek treatment if increasing. The concentrations of sugars from 5.7 to 6.4 is a serious reason for such appeals.

Renamedialog wrote about what foods can lead to diabetes.

New marker provides insights into the development of type 2 diabetes

Small chemical changes in the DNA building blocks, which may be influenceable by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes increase the risk of type 2 diabetes. Moreover, people with high blood levels of the binding protein IGFBP2 are less likely to develop this metabolic disorder. The changes in the blood are already detectable a few years prior to the onset of the disease.

According to the German Diabetes Health Report 2018, more than 5.7 million people in Germany suffer from type 2 diabetes. The affected individuals react inadequately to the hormone insulin, which leads to elevated blood glucose levels. This in turn can lead to strokes, heart attacks, retinal damage, kidney damage and nerve disorders. Since the metabolic disease develops gradually, initial damage has usually already occurred at the time of diagnosis. “In the future, our findings may help to identify risk potentials for type 2 diabetes even earlier and help to counteract the disease with preventive measures,” said Professor Annette Schürmann, head of the Department of Experimental Diabetology at the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) and speaker of the German Center for Diabetes Research (DZD).

Uncovering the molecular mechanisms

In addition to insulin, insulin-like growth factor 1 (IGF-1) is also involved in the metabolism of sugar and fat. The effect of this growth factor is weakened by binding to the IGF-binding protein 2 (IGFBP2). If the liver does not release enough IGFBP2 into the blood, the balance of the glucose and lipid metabolism may be disrupted. The research team led by Schürmann and Professor Matthias Schulze, head of the Department of Molecular Epidemiology at DIfE, therefore investigated how the diminished effect of the IGFBP2 gene could influence the development of type 2 diabetes.

Human studies show that people suffering from fatty liver produce and release less IGFBP2. Schürmann’s team observed similar effects in earlier mouse experiments, which showed that IGFBP2 levels were already reduced prior to the liver disease. This is due to the transfer of methyl groups at certain sites of the IGFBP2 DNA sequence, which inhibited the gene in the liver. These so-called epigenetic changes are caused, among other things, by lifestyle factors. Such modifications of the DNA in the IGFBP2 gene were also previously detected in blood cells of overweight people with impaired glucose tolerance.

Translational research from mouse to human studies

The interdisciplinary research team led by Schürmann and Schulze used findings from the clinic and laboratory to evaluate blood samples and data from the EPIC Potsdam Study. “This study is a good example of how translational research works: A clinical finding is taken up, analyzed mechanistically in the laboratory and finally examined in a population-wide study,” said Schürmann.

Recent analyses by the researchers indicate that inhibition of the IGFBP2 gene promotes type 2 diabetes. In addition, the team of scientists observed that leaner study participants and study participants with lower liver fat levels had higher concentrations of the protective binding protein in the blood. Higher plasma concentrations of IGFBP2 were associated with a lower risk of developing type 2 diabetes in subsequent years. “Our study confirms the hypothesis that the IGF-1 signaling pathway also plays an important role in the development of type 2 diabetes in humans,” added Dr. Clemens Wittenbecher, research associate in the Department of Molecular Epidemiology at DIfE and first author of the study.

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Caloric dinner after 6 PM threatens to diabetes

A new study by scientists from Columbia University in new York suggests that a dense, rich calories meals after 6 PM threatens the development of diabetes. Also a similar tendency to the rich on calorie dinner after 6 PM have to increase blood pressure that can adversely affect the heart.

When experts analyzed the food 12708 people aged 18 to 76 years in Latin America, revealed that more than half of them eats at dinner after 6 PM more than 30% of daily calories. The study showed that such a generous calorie dinner late in the evening threatens with unpleasant changes in the body associated with higher levels of glucose, insulin and insulin resistance.

The researchers concluded that daily caloric dense and dinner after 6 PM could face increased risk of developing prediabetes (a condition that precedes diabetes) and hypertension.

“The use of 30% or more of the number of daily calories after 6 PM on 23% increases the risk of developing high blood pressure and 19% increases the likelihood of diabetes,” concluded the authors of the project.
Earlier Magicforum wrote that peanut oil effectively promotes weight loss.

CDC: prevalence of gestational diabetes 6.0 percent in 2016

(HealthDay)—The prevalence of gestational diabetes was 6.0 percent in 2016, with a slight increase seen from 2012 to 2016, according to research published in the Nov. 2 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

Nicholas P. Deputy, Ph.D., from the CDC in Atlanta, and colleagues analyzed 2012 to 2016 National Vital Statistics System birth data to examine recent state-specific trends in gestational diabetes.

The researchers found that the crude national prevalence of preexisting diabetes was 0.9 percent among women with live births and the prevalence of gestational diabetes was 6.0 percent in 2016. The age- and race/ethnicity-standardized prevalence of preexisting diabetes was stable at 0.8 percent among 40 jurisdictions with continuously available data from 2012 through 2016, while a slight increase was seen from 5.2 to 5.6 percent for gestational diabetes.

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