Few hallmarks of the 1960s counterculture stand out like sex, drugs, and rock-n-roll—elements of a “lifestyle” that Life magazine once branded as “antithetical in almost every respect […]
Biosimilar drugs are cheaper than biologics. Are they similar enough to switch?
It took years for Elle Moxley to get a diagnosis that explained her crippling gastrointestinal pain, digestion problems, fatigue, and hot, red rashes. And after […]
Drugs that mimic effects of cigarette smoke reduce SARS-CoV-2’s ability to enter cells
Researchers have identified a potential reason why lower numbers of COVID cases have appeared amongst smokers compared to non-smokers, even as other reports suggest smoking […]
A comparison of drugs that cause injury via mitochondrial or other mechanisms
Drug-induced liver injury (DILI) is a leading reason for preclinical safety attrition and post-market drug withdrawals. Drug-induced mitochondrial toxicity has been shown to play an […]
Cocktail of prostate drugs could shrink tumours, trial shows
New prostate drug hope: Cocktail of medications could shrink tumours and cuts deaths by a QUARTER, trial shows A new combination of prostate cancer drugs […]
Repurposed drugs present new strategy for treating COVID-19
A joint research group from KAIST and Institut Pasteur Korea has identified repurposed drugs for COVID-19 treatment through virtual screening and cell-based assays. The research […]
Hepatitis C drugs boost remdesivir’s antiviral activity against COVID-19
Remdesivir is currently the only antiviral drug approved in the U.S. for treating COVID-19 patients. In a paper published this week in Cell Reports, researchers […]
Screening for SARS-CoV-2 non-structural protein 14 inhibitors
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome generates 16 distinct non-structural proteins (nsp) that constitute the enzymes and accessory proteins responsible for virus […]
Early treatment with anti-VEGF injections slows diabetic retinopathy
Early treatment with anti-VEGF injections slowed diabetic retinopathy in a clinical study from the DRCR Retina Network (DRCR.net). However, two years into the four-year study […]
New machine learning algorithm ranks drugs based on efficacy in reducing cancer cell growth
Researchers from the Queen Mary University of London have developed a machine learning algorithm that ranks drugs based on their efficacy in reducing cancer cell […]
Repurposed heart and flu drugs that protect platelets improve survival of septic mice
Despite continued improvements in antibiotics and hospital intensive care, staph sepsis -; a bloodstream infection caused by Staphylococcus aureus bacteria -; still causes severe illness […]
Biomarkers dramatically improve success rates of new cancer drugs
In recent decades there have been some big advances in developing new cancer medicines, such as Herceptin, the targeted drug to treat women diagnosed with […]
Scientists use computer simulations to identify future targets for treatment of Covid-19
University of Warwick scientists model movements of nearly 300 protein structures in Covid-19. Scientists can use the simulations to identify potential targets to test with […]
Study highlights promising opportunities that may reduce wasteful health care spending
Spending on low-value health care among fee-for-service Medicare recipients dropped only marginally from 2014 to 2018, despite both a national campaign to better educate clinicians […]