New research published in the Journal of Physiology found that otherwise healthy young people diagnosed with COVID-19, regardless of their symptom severity, have problems with […]
COVID-19 causes ‘unexpected’ cellular response in the lungs, research finds
New insights into the immune response to SARS-CoV-2 infections could bring better treatments for COVID-19 cases. An international team of researchers unexpectedly found that a […]
Make-up of gut microbiome may influence COVID-19 severity and immune response
The variety and volume of bacteria in the gut, known as the microbiome, may influence the severity of COVID-19 as well as the magnitude of […]
Large-scale cancer proteomics study profiles protein changes in response to drug treatments
Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center […]
Cells sacrifice themselves to boost immune response to viruses
Whether flu or coronavirus, it can take several days for the body to ramp up an effective response to a viral infection. New research appearing […]
Computational gene study suggests new pathway for COVID-19 inflammatory response
Analyses of lung fluid cells from COVID-19 patients conducted on the nation’s fastest supercomputer point to gene expression patterns that may explain the runaway symptoms […]
Modified clinical trial protocol created in response to urgency of COVID-19 pandemic
A new paper published online in the Annals of the American Thoracic Society describes a nimble, pragmatic and rigorous multicenter clinical trial design to meet […]
Coronavirus response isn’t helping the billion people who live in informal megacity settlements
Having ravaged some of the world’s wealthiest cities, the coronavirus pandemic is now spreading into the megacities of developing countries. Sprawling urban areas in Brazil, […]
Study finds ‘frozen’ fear response may underlie PTSD
Learned fear responses enable animals—including humans—to flee or freeze in the face of a perceived threat. But if these behaviors persist after the danger lifts, […]
Biosimilar for HER2+ breast cancer: Overall response rate matches reference trastuzumab
The trastuzumab biosimilar HLX02 achieved similar overall response rate to reference trastuzumab in women with human epidermal growth factor receptor 2-positive (HER2+) recurrent or previously […]
Signature of an ineffective immune response to cancer revealed
Our immune system is programmed to destroy cancer cells. Sometimes it has trouble slowing disease progression because it doesn’t act quickly or strongly enough. In […]
40-50% response rate for brigatinib after other next-gen ALK inhibitors
Crizotinib was the first drug licensed to treat ALK-positive non-small cell lung cancer (ALK+ NSCLC). Since then, a range of next-generation ALK-inhibitors including ceritinib, alectinib, […]
Protein content as a marker for response to therapy in brain cancer
Brain tumors vary widely in how they respond to treatment. However, early assessment of therapy response is essential in order to choose the best possible […]
Immune response to gut microbes may be early indicator of type 1 diabetes
A team of researchers with members affiliated with several institutions in Canada has found an association between children with a genetic disposition to type 1 […]