We have introduced an efficient method to superimpose eye fundus images from persons with diabetes screened over many years for diabetic retinopathy. The method is fully automatic and robust to camera changes and colour variations across the images both in space and time. All the stages of the process are designed for longitudinal analysis of cohort public health databases where retinal examinations are made at approximately yearly intervals.

In this paper a method is presented for superimposition (i.e. registration) of eye fundus images from persons with diabetes screened over many years for diabetic retinopathy. The method is fully automatic and robust to camera changes and colour variations across the images both in space and time. All the stages of the process are designed for longitudinal analysis of cohort public health databases where retinal examinations are made at approximately yearly intervals.

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