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"Rob Lowe says that once your kids leave, you pretty much never put clothes on ever again; you’re just naked all the time,” Consuelos joked. "So there’s that too!”

However, according to Ripa, she knows her kids will still stay close.

"We love each other — but we also really like each other, and we respect each other," she added. "I don’t think any amount of college or growing up will take that away from us."

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