More frequent surveillance no benefit after NSCLC resection

(HealthDay)—For patients undergoing resection for non-small cell lung cancer (NSCLC), more frequent surveillance is not associated with improved survival, according to a study published in the October issue of the Annals of Surgery.

Timothy L. McMurry, Ph.D., from the University of Virginia Health System in Charlottesville, and colleagues examined the potential correlation between the intensity of surveillance following surgical resection for NSCLC and survival. Stage I to III NSCLC patients were randomly selected for data reabstraction. Registrars documented all postsurgical imaging for patients diagnosed between 2006 and 2007 and followed for five years through 2012. A total of 4,463 patients underwent computed tomography surveillance; they were grouped based on time from surgery to first surveillance.

The researchers found that higher-stage patients underwent more surveillance. There was no correlation between more frequent surveillance and longer risk-adjusted overall survival (hazard ratio for six months, 1.16 [95 percent confidence interval, 0.99 to 1.36] and annual, 1.06 [95 percent confidence interval, 0.86 to 1.31] versus three months; P = 0.14). There was also no correlation between more frequent imaging and postrecurrence survival (hazard ratio, 1.02 per month since imaging; 95 percent confidence interval, 0.99 to 1.04; P = 0.43).

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It is estimated how many years after quitting Smoking normal health

Quitting Smoking took more than 15 years to the risk of developing cardiovascular disease have returned to the level of those who never smoked. This is indicated by the results of the preliminary research presented recently in Chicago at the Scientific sessions of the American heart Association (American Heart Association).

Previous studies have shown that the risk of cardiovascular disease in smokers is reduced a few years after they quit Smoking. However, previously it was not possible to trace the history of Smoking participants to note changes in the frequency of Smoking or evidence of relapse of Smoking.

In the new study, the researchers analyzed history of Smoking over a lifetime of about 8700 participants of the Framingham study (Framingham Heart Study), whose early studies have not yet been cardiovascular diseases. The average for the participants in the study were followed for 27 years. At the same time, the researchers compared the risk of cardiovascular disease in smokers, non-smokers and ex-smokers.

As a result, the researchers found that:

  • More than 70% of cases of cardiovascular disease in smokers or former smokers was observed in those who smoked a pack a day for 20 years.
  • Former smokers who quit within the past five years, the risk of developing cardiovascular disease fell by 38% compared with those who continued to smoke.
  • Overall it took 16 years from the date of refusal of Smoking to the risk of developing cardiovascular disease in former smokers returned to the same level as those who never smoked.

These results emphasize that some benefits of quitting can be seen during the first five years, as 38% reduced risk of heart attack and stroke compared with people who continue to smoke. We also found that the risk of cardiovascular disease remains elevated for 16 years after people quit Smoking compared with people who never smoked. The conclusion of the study is that if you smoke, now is a good time to quit, says Meredith Duncan, (Meredith Duncan), author of the study from the Medical center of Vanderbilt University (Vanderbilt University Medical Center) in Nashville, Tennessee.

Dmitry Kolesnik

Scientists were able to prove the benefits of young blood in the fight against aging

Chinese scientists from Huajumbaro University of science and technology found that plasma transfusions of young blood helps to rejuvenate the liver and its recovery after ischemia-reperfusion. This condition occurs when the cessation of blood flow in the body and is dangerous for older patients. About it reported in a press release on EurekAlert!.

In the experiment, the researchers used three groups of rats. The first animals were given injections of young blood plasma and the other got plasma from old rodents. The third group served as a control, the scientists did not carry out any interventions. Then all animals were subjected to artificially induced ischemia-reperfusion. It turned out that the animals in the first group of the liver to recover from injury much faster.

According to scientists, the results for the first time, clearly support the therapeutic and rejuvenating effect of a transfusion of blood plasma. This procedure may be useful for people, however further research is required to confirm a beneficial effect of the plasma on the liver elderly patients with poor circulation.