A treatment regimen for patients with advanced melanoma that combines the immunotherapy agents relatlimab (anti-LAG-3) and nivolumab (anti-PD-1) delayed time to cancer progression significantly more […]
Deactivating cancer cell gene boosts immunotherapy for head and neck cancers
By targeting an enzyme that plays a key role in head and neck cancer cells, researchers from the UCLA School of Dentistry were able to […]
A step forward toward immunotherapy for hematological cancers
In cancer treatment, immunotherapy helps the patient’s immune system fight cancer, for example through better recognition of the cancer cells, and it has proven effective […]
Despite COVID-19 pandemic, first patient undergoes new personalized immunotherapy
Since 2016, Bernard Thurman has undergone traditional treatments, experimental therapies and surgeries to counter the cancer within him, but nothing has successfully eradicated the disease. […]
Boosting stem cell activity can enhance immunotherapy benefits
Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active “super immune cells” with strong antitumor activity, […]
Immunotherapy for lung and other cancers may also be beneficial for rare skin cancer
Cutaneous angiosarcoma is a rare, highly aggressive skin tumor found primarily on the scalps of older White people, but based on new research from the […]
How melanoma deceives the immune system, increasing resistance to immunotherapy
The sophisticated human immune system has evolved to become an effective protection system against a great number of diseases, including cancer. The immune system recognizes […]
Increasing the effectiveness of cancer treatments: Anti-PD-L1 immunotherapy
For most people, there is no scarier diagnosis than that of cancer. While treatments including chemotherapy and radiotherapy have been used since the 1940s and […]
Immunotherapy improves survival in advanced bladder cancer patients
An immunotherapy drug called ‘avelumab’ has been shown to significantly improve survival in patients with the most common type of bladder cancer, according to results […]
Immunotherapy, steroids had positive outcomes in children with COVID-related multi-system inflammatory syndrome
Treatment with antibodies purified from donated blood—immune globulin therapy—and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to […]
Immunotherapy treatment after chemotherapy significantly slows metastatic bladder cancer
Using immunotherapy immediately after chemotherapy treatment in patients with metastatic bladder cancer significantly slowed the progression of the cancer, according to results of a clinical […]
Immunotherapy and diabetes—a game of hide and seek?
Immune checkpoint inhibitors (ICIs) are an emerging type of cancer immunotherapy that uses the immune system to attack cancer cells. However, in some patients they […]
De-TOXing exhausted T cells may bolster CAR T immunotherapy against solid tumors
A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own […]
Primary findings from first-in-human immunotherapy trial show promise in treating neuroblastoma
Neuroblastoma is the most common extracranial solid cancer in children, and patients with high-risk disease are challenging to treat. In a promising development, researchers at […]