A lot of men would be willing to give an oral contraceptives to take, if safety and tolerability are of the female contraceptive pill is comparable. An American team of researchers has now tested for the second candidate of such a pill for the man.

The active substance with the complicated name of 11-β-Methyl-19-nortestosterone dodecyl carbonate (11-β-MNTDC) combines the properties of the male sex hormone, testosterone, and progesterone, which regulates in the case of women the cycle, but also in men, in low concentrations. "This pill, which is a combination of two hormonal activities, lowers the production of sperm, while the Libido, but bleibt", Dr. Christina Wang from the Los Angeles Biomed Research Institute of the results of the study reported.

A total of 40 healthy men took part who received over 28 days of either 11-β-MNTDC in various dosages, or a Placebo. In the test group, the level of testosterone of the participants dropped significantly, without the men have reported of severe side effects. Wang, according to it, the only mild side effects such as fatigue, acne, headaches, slightly reduced sex drive or mild erectile dysfunction, but did not lead to a decrease in sexual activity. None of the participants had discontinued the study due to side effects.

Since sperm production will only be suppressed after an application by at least 60 to 90 days, effectively, was the observation period of 28 days is too short to assess the effectiveness, added Wang. The researchers are therefore planning further studies of longer duration. The Team explored with Dimethandrolon-Undecanoate (DMAU), a further prospective pill for the man. The goal was to identify at the end of the most effective and well-tolerated drug.

on/PZ/NK

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